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Immunohistochemistry in Normal Skin: Cytokeratins
Before you can use immunostains to help recognize different tumors and diseases in dermpath, you must first understand how they stain the normal structures in the skin. In this video we will discuss these various keratins and how they are expressed in the normal skin structures:
00:00 Importance of normal IHC patterns & IHC controls
02:00 CK 903
02:20 High molecular weight vs Low molecular weight keratins
06:08 Globules of keratin in dermis (likely cytoid bodies) on IHC
08:00 CK 5/6
10:50 CAM 5.2
12:58 Pancytokeratin
15:55 Mast cells staining non-specifically with various IHC stains
Content distributed here with the permission of author @JMGardnerMD on Twitter
Resource details
| Contributed by: | Pathology Portal |
| Authored by: |
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| Licence: | © All rights reserved More information on licences |
| First contributed: | 02 July 2022 |
| Audience access level: | Full user |
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