Exploring protein families and domains using InterPro

InterProprovides functional analysis of proteins by classifying them into families and predicting domains and important sites using predictive models provided by 13 different databases.

This webinar will take you through the different ways to search the InterPro website and its API to identify protein families and domains. We will explore different use cases, including how to use the InterPro sequence search functionality to identify the protein family membership, the different domains and potentially the protein function of unknown proteins. We will also explain how InterPro can be used to identify new protein domains using AlphaFold structure predictions

Who is this course for?

This webinar is aimed at students or early career researchers beginning to use bioinformatics resources in their studies/research who wish to learn more about InterPro. No prior knowledge of bioinformatics is required, but undergraduate level knowledge of biology would be useful.

This event is part of a webinar series -Molecular building blocks of life- showcasing the EMBL-EBI resources that provide data and tools for studying molecular building blocks of life at molecular level such as metabolites, DNA/RNA, proteins, and at systems level such as cells. Check outother webinars in this series.

Please note that we are not able to provide certificates of attendance for our webinars.

Outcomes

By the end of the webinar you will be able to:

• Summarise the concept of protein classification of InterPro and how it may be useful in your research
• Analyse the results of a protein sequence search to identify protein families and domains
• Describe how AlphaFold protein structure predictions assist in domain boundaries determination and are useful to identify new ones