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Epidermodysplasia verruciformis (EDV) 101 video
Epidermodysplasia verruciformis (EV or EDV) is an unusual form of verruca plana (flat wart) that is caused by infection with various types of HPV (types 5 and 8 are most common). Rare cases are widespread and due to an autosomal recessive inherited mutation in the EVER1 or EVER2 gene, which makes the patient more susceptible to these particular types of HPV. Much more often, EDV presents as solitary sporadic lesions (epidermodysplasia verruciformis acanthoma) or as tiny incidental foci seen in the background epidermis on biopsies or excisions performed for some other reason.
Note: the so-called "tree man" syndrome is supposedly epidermodysplasia verruciformis, but I believe it must be a different variant than the classic forms of EDV I show in this video. Although I've never personally seen a biopsy from a patient with the clinical "tree man" appearance, so I don't know for sure.
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| Contributed by: | Pathology Portal |
| Authored by: |
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| Licence: | © All rights reserved More information on licences |
| First contributed: | 04 August 2022 |
| Audience access level: | Full user |
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