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Home Pathology Portal Genetics and Genomics Omics techniques and their application to genomic medicine Current methodologies to assess the transcriptome to include RNA expression profiling (expression array) and RNA sequencing.
Current methodologies to assess the transcriptome to include RNA expression profiling (expression array) and RNA sequencing.
Pathology Portal

Explore the known protein space through UniProt Archive and Clusters

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UniProt Archive (UniParc) is the most comprehensive, non-redundant protein sequence database available. Its protein sequences are retrieved from predominant, publicly accessible resources. To avoid redundancy, each unique sequence is stored only once with a stable protein identifier. As a result, performing a sequence search against UniParc is equivalent to performing the same search against all databases cross-referenced by UniParc.

UniProt Reference Clusters (UniRef) provides clustered sets of sequences from the UniProt Knowledgebase (UniProtKB) and selected UniParc records to obtain complete coverage of sequence space at several resolutions while hiding redundant sequences. The reduced redundancy increases the speed of similarity searches and improves detection of distant relationships.

Who is this course for?

This webinar is for individuals who wish to learn more about UniParc. No prior knowledge of bioinformatics is required, but an undergraduate level knowledge of biology would be useful.

DOI: 10.6019/TOL.UniParc-w.2019.00001.1

Resource details

Contributed by: Pathology Portal
Authored by: Hermann Zellner, The European Molecular Biology Laboratory-European Bioinformatics Institute's (EMBL-EBI).
Borisas Bursteinas, The European Molecular Biology Laboratory-European Bioinformatics Institute's (EMBL-EBI).
Mahesh Prahladan, Pathology Portal
Licence: Creative commons: Attribution-NonCommercial 4.0 International More information on licences
First contributed: 23 May 2024
Audience access level: General user

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