Pathology Portal

Finding and interpreting protein structure and function data using PDBe-KB

Not yet rated

Proteins are the workhorses of the cell, responsible for most biological functions. Though we can group related proteins through sequence similarity, it is the 3-dimensional structure of these proteins that determines the functions of these molecules of life. Therefore, knowledge of protein structure, and its relation to additional biological context, can help us create a more complete understanding of how a protein works.

PDBe-KB (https://pdbe-kb.org) is an open, collaborative data resource, which aims to support the access and integration of structural biology data helping users to easily generate biological insights. The Aggregated Views of Proteins, provided through PDBe-KB, provide a unique way to display all the relevant structure and function data for a specific protein, in one place. This allows us to determine trends across these structures, including common binding and interaction sites, and identification of different conformations of the protein.

This webinar will give an introduction to the PDBe-KB Aggregated Views of Proteins and how they can be used to access and interpret structure and function data.

This event is part of a webinar series -Molecular building blocks of life- showcasing the EMBL-EBI resources that provide data and tools for studying molecular building blocks of life at molecular level such as metabolites, DNA/RNA, proteins, and at systems level such as cells.

  • Navigate and utilise tools on PDBe-KB webpages to get an overview of available structural and functional information on your proteins of interest
  • Visualise superposed protein chains clustered by structural similarity for any protein in PDB
  • Download the relevant data for your protein of interest

Resource details

Contributed by: Pathology Portal
Authored by: Joseph Ellaway, The European Molecular Biology Laboratory-European Bioinformatics Institute's (EMBL-EBI).
Marcelo Querino, The European Molecular Biology Laboratory-European Bioinformatics Institute's (EMBL-EBI).
M Prahladan, Pathology Portal
Licence: Creative commons: Attribution-NonCommercial 4.0 International More information on licences
First contributed: 01 June 2024
Audience access level: General user

Ratings

0 ratings

Not yet rated
5 star
0%
4 star
0%
3 star
0%
2 star
0%
1 star
0%
Report an issue with this resource

You may report a resource, for example, if there is an issue with copyright infringement, breach of personal data, factual inaccuracies, typing errors or safety concerns. The type of issue will determine whether the resource is immediately removed from the platform or if the contributor is asked to make amendments. You can report a resource from the resource information page or by contacting the Learning Hub support team.

You can contact the Learning Hub support team by completing the support form or if you have a general enquiry you can email enquiries@learninghub.nhs.uk.