SCI Education Programme

Neurogenic Bowel Dysfunction in Patients with Spinal Cord Injury and Multiple Sclerosis—An Updated and Simplified Treatment Algorithm (PDF)

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Abstract: Neurogenic bowel dysfunction (NBD) is a common condition in individuals with spinal
cord injury (SCI) or multiple sclerosis (MS). It usually entails constipation, difficult evacuation of
the rectum, and fecal incontinence (FI); often in combination. It is highly burdensome for affected
patients and is correlated with poor quality of life. The current treatment algorithm, or treatment
pyramid, does not completely correspond to actual clinical practice, and the known and classical
pyramid contains both treatments still in their experimental stage as well as several treatments which
are not available at all treatment centers. Thus, an updated treatment algorithm is called upon, and
the authors of this paper therefore propose a simplified version of the treatment pyramid, aiming to
guide clinicians in treating NBD.

Citation: Magnuson, F.S.;Christensen, P.; Krassioukov, A.;Rodriguez, G.; Emmanuel, A.;Kirshblum, S.; Krogh, K. Neurogenic Bowel Dysfunction in Patients withSpinal Cord Injury and Multiple Sclerosis—An Updated andSimplified Treatment Algorithm. J.Clin. Med. 2023, 12, 6971.https://doi.org/10.3390/jcm12226971

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Contributed by: SCI Education Programme
Authored by: Fredrika S. Magnuson
Peter Christensen
Andrei Krassioukov
Gianna Rodriguez
Anton Emmanuel
Steven Kirshblum
Klaus Krogh
Authored on: 7 November 2023
Licence: Creative Commons: Attribution-NonCommercial-ShareAlike 4.0 International More information on licences
First contributed: 03 June 2025
Audience access level: Full user

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