Pathology Portal

An update on DNA mismatch repair immunohistochemistry webinar

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The use of DNA mismatch repair (MMR) immunohistochemistry (IHC) has expanded over recent years. It is now one of the recommended methods for Lynch syndrome screening in colorectal and endometrial carcinoma and has utility in the prediction of tumour response to checkpoint inhibitor therapy. This webinar will provide a basic refresher of the science behind DNA MMR proteins and the staining patterns most commonly encountered in DNA MMR IHC, including some common practical issues.

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Contributed by: Pathology Portal
Authored by: Professor Adrian C Bateman, Consultant Histopathologist
Licence: © All rights reserved More information on licences
First contributed: 23 January 2026
Audience access level: General user

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