Pathology Portal

SO5 E202 - Episode 202: AI vs. Superbugs: Can AI Help?

Not yet rated

Antimicrobial resistance (AMR) continues to grow as a global health threat, making infections harder to treat and leaving fewer options for patients. The need for new antibiotics is an urgent matter — but traditional discovery methods are slow and limited. In this episode of Let’s Talk Micro, Luis is joined by Dr. James Collins, professor at MIT and researcher at the Broad Institute, who is leading efforts to apply AI to antibiotic discovery. We discuss how his team used deep learning to uncover promising new compounds, including NG1 and DN1, which showed activity against drug-resistant Neisseria gonorrhoeae and Staphylococcus aureus. We also talk about the challenges of bringing discoveries from computer models to the clinic, and what this approach could mean for the future of the fight against superbugs.

Link to study: https://www.cell.com/cell/abstract/S0...

Check out the website: https://www.letstalkmicro.com/

Questions? Feedback? Send those to letstalkmicro@outlook.com

Resource details

Contributed by: Pathology Portal
Authored by: Luis Plaza, Let's talk Micro
Licence: © All rights reserved More information on licences
First contributed: 10 September 2025
Audience access level: General user

Ratings

0 ratings

Not yet rated
5 star
0%
4 star
0%
3 star
0%
2 star
0%
1 star
0%
Report an issue with this resource

You may report a resource, for example, if there is an issue with copyright infringement, breach of personal data, factual inaccuracies, typing errors or safety concerns. The type of issue will determine whether the resource is immediately removed from the platform or if the contributor is asked to make amendments. You can report a resource from the resource information page or by contacting the Learning Hub support team.

You can contact the Learning Hub support team by completing the support form or if you have a general enquiry you can email enquiries@learninghub.nhs.uk.