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Home Pathology Portal Genetics and Genomics STP curriculum - Genomics Cancer Genomics Introduction to Haematology Clinical Features Myeloid disorders
Myeloid disorders
Pathology Portal

Assessment- Clonal Haematopoiesis and Clonal Cytopenias of Uncertain Significance (CCUS)

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The presentation focuses on clonal haematopoiesis (CH) and clonal cytopenias of uncertain significance (CCUS), highlighting their role in the development of haematological malignancies and the importance of early identification and management. The presentation begins by outlining the classification of myeloid neoplasms, referencing the World Health Organization’s (WHO) 5th edition (2022) and 4th edition (2017) classifications. These classifications encompass acute myeloid leukemia (AML), myelodysplastic syndromes (MDS), chronic myelomonocytic leukemia (CMML), and classical myeloproliferative neoplasms (MPNs) such as essential thrombocythemia (ET) and polycythemia vera (PV).

Contributed by: Pathology Portal
Authored by: Dr Emily Mitchell, Cambridge University Hospitals NHS Foundation Trust, Consultant in Haemato-Oncology Diagnostic Service,(HODS)
Dr Pallota Perinde, Pathology Portal
Licence: Creative commons: Attribution-NonCommercial 4.0 International More information on licences
First contributed: 03 December 2024
Audience access level: General user

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