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Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC)
DGONC is a relatively new tumour entity with a distinct methylation profile. It now features in the WHO CNS Tumour Classifcation 2021. It is proposed as a neuroepithelial tumour characterised by variably differentiated cells frequently showing perinuclear haloes, scattered multinucleated cells and nuclear clusters. Monosomy of chromosome 14 is a frequent finding. This paper presents a small case series of these tumours.
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| Contributed by: | Pathology Portal |
| Authored by: |
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| Licence: | © All rights reserved More information on licences |
| First contributed: | 25 July 2022 |
| Audience access level: | Full user |
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