Exploring somatic mutations in cancer with the COSMIC database and analysis tools

COSMIC(the Catalogue of Somatic Mutations in Cancer) helps the global cancer research community conduct their science faster and better by presenting easy to understand, streamlined, and quality filtered data on cancer mutations.

With 23 million genomic variants, expertly curated from nearly 30,000 publications, covering 6,800 precise forms of human cancer, COSMIC is the world’s largest manually curated database of somatic mutation information relating to human cancers. This vast breadth and depth of high quality data is the gold standard, relied upon by academic research and industry alike, including pharmaceutical, drug discovery and biotech companies.

This webinar will provide an introduction to COSMIC, our process, and demonstrate the vast range of data and analyses available via our multiple tools and projects. We will focus particularly on two of our newer projects: Cancer Mutation Census and Actionability, which will be freely available for non-commercial download as of 29 November 2022. We will also provide an opportunity for questions and hope that by the end of the webinar, you will feel confident in exploring COSMIC’s tools and understand how they can add value to your work.

Outcomes

By the end of the webinar you will be able to:

• Describe the depth and breadth of data within COSMIC
• Identify how COSMIC data can be used to add value to your work
• Explore COSMIC’s datasets and webpages

DOI: 10.6019/TOL.cosmic22-w.2022.00001.1

Speakers

• Rebecca White
  Wellcome Sanger Institute
• Steven Jupe
  Wellcome Sanger Institute
• Jennifer Wilding
  Wellcome Sanger Institute
• Michael Starkey
  Wellcome Sanger Institute
• Helder Pedro
  Wellcome Sanger Institute